Introduction: Coronary artery bypass grafting (CABG) surgery remains the most common procedure in adult cardiac surgery for coronary artery disease. Objectives: The main objective of the study is to find the infection in open vs endoscopic saphenous vein harvest for patients undergoing CABG surgery. Material and method: This comparative analysis was conducted at Rawalpindi Institute of Cardiology, Armed Forces Institute of Cardiology, Rawalpindi and Shifa International Hospital, Islamabad from October 2019 to 2021. The data was collected with the permission of the ethical committee of hospital. The data was collected with the permission of the ethical committee of the hospital. Patients undergoing CABG or combined valve/CABG with EVH and OVH were differentiated from each other in the MHCCSR as of the start of the study period. The OVH was performed by either a continuous, longitudinal incision or through multiple smaller incisions. Results: The data were collected from 122 patients, from these 22 patients were not extubated and none of them survived. The most common indication for surgery was myocardial revascularization (30.6%), followed by valve replacement (22.7%) and thoracic aortic aneurysm repair. Practical implication: EVH is now considered not to be the best method in CABG surgery. Conclusion: It is concluded that, patients undergoing CABG surgery with EVH presented with worse systolic function and more recent myocardial infarction. Keywords: CABG, Procedure, EVH, Systolic, Myocardial infarction, Endoscopic

Introduction: Treatment for coronary artery disease (CAD) includes medical therapy, percutaneous coronary intervention (PCI) and coronary artery bypass grafting. Objectives: The main objective of the study is to find the comparison of MIDCAB vs open off-pump procedure CABG for single vessel coronary disease. Material and methods: This comparative analysis was conducted at Rawalpindi Institute of Cardiology, Armed Forces Institute of Cardiology, Rawalpindi and Shifa International Hospital, Islamabad from October 2019 to 2021. Informed consent was taken from all the patients before collecting the data. Patients in the MIDCAB group received sub-station hybridization to treat the diseased vessels except the left anterior descending (LAD). Patients in the OPCAB group were placed in the supine position, and combined intravenous inhalational anaesthesia was given; then, single-lumen endotracheal intubation was performed through the median incision. Results: The data were collected from 100 coronary artery disease patients. The mean age of the study patients was 54.4±10.6 years. Cigarette smoking was much more common in men than in women (32.6% vs. 0, p<0.001). The serum levels of creatinine, uric acid, and cTAS were significantly higher in men than in women (0.9±0.2 vs. 0.7±0.1, 7.6±2.1 vs. 6.8±2.3, and.0.4±0.0 vs. 0.3±0.1, respectively; p<0.001). Conclusion: It is concluded that MIDCAB procedures can be performed with similar safety as OPCAB procedures. Postoperative outcomes in terms of mortality were satisfactory, rendering this procedure at least as safe as the option of OPCAB. Practical implications: MIDCAB is considered to be the safe procedure and we may practically use this method. Key words: MIDCAB, OPCAB, Mortality, Coronary Artery Diseases, Procedures