The results of the study showed the effect of Leucaena leucocephala, Platanus orientalis and Populus alba woods, Concentrations were 0.0025, 0.005, and 0.01% in the Microcerotermes diversus Silv. workers response for Antibiotic Amoxicillin and Nidazole, by spraying and dipping methods, in medium-contrast ratios of insect mortality on the three kind of wood, as it reached: 63.10%, 48.75% and 50.10% respectively by spray, which gave an average rate of mortality after six days 99.38%. While the results showed an increase in the average mortality rates of Termites with an increase in concentration (0.0025, 0.005 and 0.01%), reaching 42.73, 54.60 and 64.70%, respectively, while Nidazole had a clear superiority in the average percentage of deaths of Microcerotermes diversus Silv. , as it reached 61.17%, while it reached 46.86% for amoxicillin. As for the results of the dipping method, there was no significant difference in wood type in the average mortality rates, as it reached 53.62, 56.86 and 51.49%, respectively, while the highest average mortality rate after four days of exposure was 88.23%. Concentrations reached 41.50, 54.73 and 65.75%, respectively, Amoxicillin and Nidazole did not have a significant difference in the mean Termites mortality as it reached 53.92 and 54.06%.