Honey one of honeybee product that consider main food in many meals and have vital role in treatment a lot of medical problems. However, can be consider source of problems to human being around the world. Although the case of honey anaphylaxis very rare but so dangerous and may be life-threatening. In Iraq, I investigated and documented one case with honey allergy by skin prick-prick test. A patient with honey allergy has symptoms from mild to severe complications. Medical centres have no any background about this type of allergy, therefore it important to explain this case to prevent mis-diagnosis.