Urticaria is a kind of skin rash that sometimes caused by allergic reactions. Acute viral infection, stress, pressure, exercise and sunlight are some other causes of urticaria. However, chronic urticaria and angioedema could be either idiopathic or caused by autoimmune reaction. They last more than six weeks and could even persist for a very long time. It is thought that the level of C-reactive protein CRP increases and the level of Erythrocyte sedimentation rate (ESR) decreases in patients with chronic urticaria. Thirty four patients with chronic or recurrent urticaria were selected for the treatment with wet cupping. Six of them, because of having a history of recent infection/cold urticaria, were eliminated and the remaining 28 were chosen for this study. ESR and CRP were measured in these patients aged 21-59, comprising 12 females and 16 males, ranged from 5-24 mm/h for ESR with a median 11 mm/h and 3.3-31.2 mg/L with a median of 11.95 mg/L for CRP before and after phlebotomy (250-450mL) which was performed as a control for wet cupping therapy. Three weeks after phlebotomy, wet cupping was performed on the back of these patients between two shoulders and the levels of ESR and CRP were measured again three weeks after wet cupping. The changes were observed in the level of CRP and ESR after phlebotomy being negligible. However, the level of CRP with a median 11.95 before wet cupping dramatically dropped to 1.1 after wet cupping. The level ESR also with a median 11 before wet cupping rose to 15.5 after wet cupping therapy. The clear correlation between the urticaria/angioedema and the rise of CRP was observed as was anticipated. No recurrence has been observed on twenty five of these patients and three of them are still recovering from the lesions.
Currently study was a double-blind clinical trial in terms of ointments with different contents and the variables such as sex, drug charges, occupation, age, number of lesions, patients, lesions location, time of manifestation, lesion size and methods of treatment and recovery time. In addition, total patients under studied were 100 people in dermatology clinic of Farshchian hospital of Hamadan in Iran that they were divided into two groups. The first group (A) contained of 68 individual who were divided into three groups which used sanseveria extract with different percentage of containing 5, 10, and 20%. Further, the second group (B) included 32 patients who used from other methods of treatment were divided into three groups. In one group12 patients have been treated by using salicylic acid, in the other groups 12 individuals used from electro cautery and 8 patients were used of the corn plasters method. In addition, 116 patients in this study were in the range of 7 to 57 years of age. In fact 100 of them have used the drug correctly while 16 patients were excluded due to wrong usage. Also the plant (Sansevieria Trifasciata) was prepared in Hamedan Research Center from plant by dried extracts method. Finally, the results were analyzed statistically using SPSS software. In conclusion, based on the results of significant impact on the treatment of corns, all patients (100%) in the first group have been treated, additionally all participants in the study were improved within 4 weeks such that the recovery time for the 5% ointment was 25 days, while for 10% and 20% ointment was 15 and 10 days respectively.
H. pylori infection is one of the most common infections in the world so that the aim of this study was to evaluate the antimicrobial P. Atlantica Kurdica gum in the eradication of H. pylori. This study is a randomized clinical trial; Patients with positive Urea Breath Test and symptoms of dyspepsia were entered. Patients were randomly divided into four groups. Group A: three drugs including 500 mg of Amoxicillin twice a day (bd), Clarithromycin 500 mg bd and Omeprazole 20 mg (bd) and Group B: Group A drugs plus the capsule containing 1 g of powdered P. Atlantica Kurdica gum (bd). In Group C: the capsule containing 1 g of powdered P. Atlantica Kurdica gum (bd) and Group D: this group took placebo-containing capsule (bd) for 14 days respectively. Dyspeptic symptoms before and after healing period and the UBT results two days before the start of treatment and 30 days after the completion were compared in 4 groups. Patients were not statistically significant difference from each other in the four groups regarding the demographic situation. Moreover, H. pylori eradication rate was 19/24 in Group A, 18/24 in Group B, 10/23 in Group C and 2/24 in Group D. Relieving symptoms of dyspepsia in Groups B and C were significantly higher than in Group D (P=0.025 and p=0.006 respectively). P. Atlantica Kurdica significantly led to the treatment of dyspepsia symptoms and H. pylori eradication.
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