Purpose This paper aims to propose an integrating model for creating virtual libraries in Iranian universities of medical sciences. Design/methodology/approach This study was conducted with an analytic survey method. The statistical population comprised 66 Iranian universities of medical sciences, of which 59 libraries participated in the study. A researcher-made checklist was used for data collection. To ensure the accuracy of data, interviews and, in some cases, observations were also performed. Statistical estimates, including frequency, percentage, cumulative frequency and diagrams, were used for data analysis, and the system analysis method was used for modeling. Findings Results demonstrated that the library software programs of the studied universities of medical sciences do not have desirable interoperability capabilities. Only Azarsa program can exchange information with other systems. In terms of metadata and its standards, the studied libraries use programs with various standards, with MARC and Dublin Core standards being the most frequently used ones in the studied sample. Originality/value The model proposed here for integration is a hybrid model which can translate metadata standards and use the Z39.50 and OEI protocol to transfer data.