Data Envelopment Analysis approach was employed to evaluate the performance of 18 star hotels in Lu ' an area and Tobit Regression Model employed to explore the interrelation between operation efficiency and relevant economic data and finally spatial distribution characteristics of star hotels' operation efficiency were discussed. The main conclusions are as follows: (1) Hotels with high overall technology efficiency are characterized by spatial convergency in Lu ' an City. Pure technology efficiency of star hotels is comparatively high and scattered across the area. Spatial distribution of scale technology efficiency is featured with gradual diffuseness from center to periphery. Star hotels overall are operating in an area of increasing return to scale and evenly distributed across the area. (2) Microeconomic factors affecting star hotels' operation efficiency include tourist arrivals, room occupancy rate, operational income, area of construction, average room rate, and room numbers while macroeconomic factors are numbers of administrative department, numbers of corporations, numbers of staff and average wage.