With the growing power dissipation of information and telecommunication equipments, more concerns should be put on the cooling issues due to the reliability and OPEX requirements. This paper describes a fast optimizing cooling solution for the existing COl DC. As an important analysis approach, CFD simulation aims to improve the heat dissipation condition and the energy saving. With the application of CFD, lots of benefits from the fast optimization analysis can be obtained. In the paper, the local hot spots are firstly found out and solutions for these hot spots are proposed to keep the equipment operating in a proper environment and to guarantee the operation reliability. Then the layout of CO/DC is optimized to enhance the efficiency of the cooling system. Following the CFD analysis, several optimized solutions are presented. With the comparison of the results of different solutions in the experiment, the best one can be identified to be applied in a similar practical situation.