Objective: This study was designed to determine the relationship between metabolic syndrome as a risk factor for colorectal cancer. Background: Overweight and obesity are leading risks for global deaths. Although the increase in obesity over the last 35 years has been most dramatic in the US and western industrialized countries, similar trends have also been seen in urban areas of many developing countries. There are multiple common health consequences of an elevated body mass index, including risk for several metabolic disorders, some cancers and ultimately increased mortality Patients and methods: A case control study was carried out on 150 patients 100 cases with colorectal cancer (CRC), and 50 healthy age and sex matched controls. The patients were randomly selected from those attending