No abstract

Visceral leishmaniasis (VL) is considered one of the endemic diseases in Iraq, and due to the distinction of the anti-leishmaniasis treatments currently used by their many side effects in addition to their toxicity to the human body, as well as the length of treatment period, and the problems they cause to the digestive system, Salvia officinalis (Saga) was used as a natural preventive treatment against leishmaniasis. Because of its therapeutic properties for many health symptoms, including heart attacks, ulcers, and cancerous tumors, in addition to its antibacterial and antimicrobial nature, the current study aimed to know the inhibitory activity of plant extracts and the volatile oil of Salvia officinalis on the life of Leishmania donovani parasite, using the colorimetric test (MTT assay, to measure toxicity) promastigote parasitoid cells, six concentrations of the aqueous extract and plant emulsion of the mentioned plant were prepared (6.25, 12.5, 25, 50, 100, 200) g/mlµ, the concentrations of the volatile oil were (31.25 ,62.5, 125, 250, 500 1000) g/mlµ, The results indicated that under the influence of treatment with the three drug spectra of Salvia officinalis, there were noticeable differences in the inhibitory percentage for each drug spectrum.

Visceral leishmaniasis (VL) is a parasitic disease transmitted by biological vectors and caused by infection with the parasites of Leishmania donovani complex. After malaria, VL is the second most deadly parasitic disease in the world if not treated early in the infection,A survey study was conducted that included 252 people suspected to having visceral leishmaniasis, were reviewed in hospitals of Karbala governorate at Al-Hussein Teaching Hospital, Al-Hindiya Hospital, Ain Al-Tamr General Hospital, Al-Hussainiya Hospital, and Children’s Hospital during January 2021  to June of the same year,After diagnosing cases by doctors specializing in pediatric and internal diseases, as the diagnosis was based on the bone marrow examination of patients, out of 252 suspected cases of visceral leishmaniasis, 17 individuals were confirmed to have VL leishmaniasis distributed among the above-mentioned hospitals, the current study reviewed the category data  Age, gender and prevalence areas by geographical area and months of infection.