Cardiology interventions remain to be complex and difficult to understand by the general people. Consent requirements have become gradually challenging in parallel to the rise of autonomy as a dominant principle in biomedical ethics in addition to the complexity of cardiology intervention. Studies showed that patients have suboptimal understanding of the procedural risks and benefits.Many novel elucidations have been offered to enhance informed consent, many of which have narrowed, although not eradicated, the gap in attaining proper informed consent goals and objectives. The current review will discuss the up to date available studies that have investigated this important subject in cardiology.