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A fatal case of propranolol intoxication is described. The patient had ingested 3-5 g of the drug and probably no other drugs. Gastric lavage could not be performed due to some kind of obstruction in the distal part of the oesophagus. At autopsy, the oesophagus was normal, and a spasm due to j3-blockade is suggested. Epileptiform seizures resistant to treatment with diazepam and barbiturates were frequent and probably not solely caused by cerebral ischaemia.

Review: interactive, but not didactic, continuing medical education is effective in changing physician performance Davis D, Thomson O'Brien MA, Freemantle N, et al. Impact of formal continuing medical education. Do conferences, workshops, rounds, and other traditional continuing education activities change physician behavior or health care outcomes ? JAMA 1999 Sep 1;282:867-74.