Besides exhibiting direct microbicidal properties, antimicrobial peptides also display various immunomodulatory functions, including keratinocyte production of cytokines and chemokines, proliferation, migration and wound healing. Recently, a novel antimicrobial peptide named AMP-IBP5 (antimicrobial peptide derived from insulin-like growth factor-binding protein 5) was shown to exhibit antimicrobial activity against numerous pathogens, even at concentrations comparable to those of well-known antimicrobial peptides, such as human b-defensins and LL-37. However, the immunomodulatory role of AMP-IBP5 in cutaneous 1417 A soft, flexible, battery-less, and wearable pressure sensor with wireless communication for therapeutic compression garments: Bench validation and preliminary in vivo testing
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