Objective. To describe and assess the hospital drug control system’s measures. Methods. From 2017 to 2019, examine the changes in medication percentage, important monitoring drug amount, top 10 medications amount, and usage rate of prophylactic antibiotics for type I incisions. Results. The proportion of pharmaceuticals remains below 30%, the number of significant monitoring drugs has decreased, the top ten drugs have shifted from adjuvant to therapeutic drugs, and the use of prophylactic antibiotics for type I incisions has decreased by 10%. Conclusion. The percentage of medications that met requirements by using the drug control system has steadily decreased, and the number of pharmaceuticals for important monitoring pharmaceuticals has steadily decreased, in accordance with national medical insurance policy, as well as improved rational drug usage.