Introduction: Paediatric cancer is a potentially curable disease and its prognosis has been linked to several factors, such as nutritional status. The impact of malnutrition on these patients, either by overnutrition or undernutrition, varies and its relationship with outcomes is inconsistent. This study was conducted in order to determine the frequency of malnutrition in children with haematolymphoid malignancies at the time of diagnosis, as well as during treatment and to also investigate its relationship with the development of infections and death. Materials and Methods:A retrospective cohort study of 191 children with a recent diagnosis of a haematolymphoid malignancy. The risks and nutritional classification were determined using anthropometry, follow-ups were conducted for up to 24 months and the presentation and frequency of infections and/or death were also recorded. Bivariate and multivariate analyses were conducted using binomial logistic regressions, for death and infection outcomes during follow-up. Survival analysis was conducted for various factors and types of cancer.Results: 83.7% of children had a sufficient nutritional classification at diagnosis, 6.8% had malnutrition by undernutrition and 9.4% by overnutrition. 83.8% had at least one infectious complication during follow-up and 47.1% had ≥ 3. This percentage increased to 69.2% when configuring it in the malnutrition by undernutrition group. 18.3% of patients died. When configuring the mortality, the percentage was greater in patients with Acute Myeloid Leukaemia (AML) (57.1%) and malnutrition by undernutrition (30.7%). The multivariate analysis for the outcome of death, only showed a statistically significant variable (AML odds ratio = 26.52; confidence interval = 1.09-643.24; p = 0.04). Conclusion:No statistically significant relationship was found between the nutritional status of children with haematolymphoid neoplasms, and outcomes such as infections or Research
RESUMENIntroducción: La punción aspiración con aguja fina ha desempeñado un papel esencial en la evaluación del paciente con nódulo tiroideo, siendo un método rápido, mínimamente invasivo y de bajo costo. El objetivo de este estudio fue evaluar la precisión diagnóstica de la punción aspiración con aguja fina en lesiones tiroideas, contrastando sus resultados con los hallazgos histopatológicos obtenidos en la pieza quirúrgica. Discusión: La punción aspiración con aguja fina de tiroides es una prueba sensible, específica y con una buena precisión diagnóstica. Los datos obtenidos son comparables con los hallados en estudios previos similares.
A 7-year-old Black girl from rural Colombia was admitted with 5 days of right elbow pain, fever, asthenia, hyporexia, and coluria. She presented with contusive trauma of the aforementioned elbow 2 months before admission. She had tachycardia (144/minute), fever (38 C), tachypnea (75/minute), icterus, respiratory distress, hepatosplenomegaly, and diffuse abdominal pain. Right elbow erythema, edema, and pain were evident. The initial complete blood count test revealed thrombocytopenia (76,000/uL and 5,100/uL leukocytes), anemia (hemoglobin [Hb], 4.3 g/dl), cholestasis, and discrete elevation of the aminotransferase levels (total bilirubin, 14.63 mg/dl; direct bilirubin, 10.3 mg/dl; aspartate transaminase, 175 U/ liter; alanine aminotransferase, 128 U/liter). Because of symptomatic anemia, she received a red blood cell transfusion.Her mother reported a history of jaundice and anemia during pregnancy, without a specific diagnosis. High-flow oxygen, fluid resuscitation, empiric broad-spectrum antibiotics (vancomycin and ceftriaxone), and vasopressors were initiated. The anemic syndrome was progressive and required multiple red blood cell transfusions. Viral hepatitis (A, B, C) and
Balantidium coli es el protozoario más grande y el único parásito ciliado que infecta a los seres humanos. Es el causante de la balantidiasis, enfermedad adquirida por los humanos por transmisión fecal-oral desde su hospedero habitual: el cerdo. Reportamos el caso de una escolar inmunocompetente, que presentó peritonitis por perforación intestinal, con ulceración perianal secundaria a poliparasitismo por Balantidium coli, Enterobius vermicularis y Trichuris trichiura. Esta es una complicación poco frecuente, potencialmente prevenible y con tasas de mortalidad extremadamente altas. La paciente requirió 8 intervenciones quirúrgicas.
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