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Background: COVID-19, caused by the coronavirus, was declared a global pandemic by the WHO on March 11, 2020. The COVID-19 pandemic hit India, similar to the world, reporting its first case in March 2020. After the first wave, the second wave in India started on March 2021. The impact of the second wave was huge on all tertiary care centers, especially psychiatric care centers, compared to the first wave of COVID-19. Aim: The aim of this study is to study the impact of COVID-19 on psychiatric patients at a tertiary psychiatric hospital in Telangana state of South India. Methodology: A retrospective chart review of all patients who got infected with COVID-19 during the second wave was done. We screened all the inpatient cases who were under admission during the second wave. For the study, a semi-structured intake pro forma was used. Sociodemographic variables, clinical variables, treatment variables, and outcomes of COVID-19-infected psychiatric patients were studied. Results: The current article compiles the management of the COVID-19 outbreak in the Institute of Mental Health in inpatient care and the challenges and experiences during the management of psychiatric inpatients with COVID-19 in a tertiary care center in Telangana.

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