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An experiment was conducted to study the efficiency of inclusion of neem, turmeric, vitamin E and its combinations on performance and hematological parameters for a period of six weeks with 288 day old Raja II broiler chicks. Basal diet was supplemented with Azadirachta indica (Neem 8g/kg feed), Curcuma longa (Turmeric 2g/kg feed) and Vitamin E 0.2g/kg feed) individually and in combination to form eight test diets. Each test diet was fed ad libitum for 42 days. The result of the present stumdy identified no significant difference in body weight of chicks fed with supplemented diets. Whereas, addition of either neem alone or in combination with turmeric and vitamin E induced significant growth depression in birds compared to control birds. Supplementation of neem, turmeric, Vitamin E and their combinations in broiler diets did not exhibit any significant effect on feed intake and feed conversion ratio during all the weeks of age. The percentage livability of birds under different treatments was statistically non-significant. Hematological parameters in broilers revealed that the hemoglobin concentration in neem fed group was significantly (P<0.05) higher (10.5 g/dL) when compared to turmeric fed group (9.85 g/dL), otherwise diet containing turmeric alone recorded lowest value of hemoglobin. Feeding of neem alone and its combination with turmeric and vitamin E increases significantly PCV values as compared to control. The supplementation of turmeric or vitamin E alone to basal diet did not significantly change PCV values.

Our novel design can eliminate the preservative induced toxicity from eye drops thereby impacting hundreds of millions of patients with chronic ophthalmic diseases like glaucoma and dry eyes.

Objective: The aim of the study was to prepare the jaggery using plant mucilage as clarificants and to evaluate the bioactivity of jaggery by determining total phenols, total flavonoids, reducing power, antibacterial activity, and antihelmintic activity.Methods: Jaggery was prepared from sugarcane variety Co-80632 using five plant mucilage as clarificants, namely Aloe vera, flax seeds, fenugreek, purslane, and malabar spinach at three different concentrations, i.e., 0.1%, 0.2%, and 0.4% of raw sugarcane juice. The characteristic bioactivities such as total phenol content by Folin–Ciocalteu method, flavonoids content by spectrophotometer method, reducing power assay by measuring the absorbance at 700 nm, antibacterial activity by well-diffusion method, and antihelmintic activity by in vitro were determined.Results: The highest total phenolic content was observed in jaggery prepared using plant mucilage clarificant of A. vera (JAV4 [3.68±0.02]) and Fenugreek seeds (JFG4 [3.61±0.02]) at 0.4% followed by them at 0.2% and 0.1% concentration, respectively. Similarly, a significant amount of total flavonoids content was elevated only in 0.4% plant mucilage clarificants of Aloe vera-treated experimental group jaggery (0.73±0.01) compared to control (0.61±0.02). Further, the antioxidant activity of jaggery was evaluated by reducing power. The increased absorbance at 700 nm indicated the presence of reducing power. At 10 mg/ml concentration, an absorbance unit of 1.93 and 1.80 was observed for jaggery prepared using 0.4% concentration of A. vera and fenugreek seed mucilage clarificants. Antihelmintic activity of jaggery showed dosage depended on the pattern where with the increase in the concentration of mucilage, the antihelmintic activity enhanced. A. vera mucilage showed maximum antihelmintic activity at 0.4% concentration with paralytic time (28.6 min) and death time (39.6 min).Conclusion: Jaggery prepared using plants mucilaginous clarificants is the richest source of polyphenols such as phenolic acids and flavonoids, thereby contributed to the enhancement of bioactivity such as antioxidant, antibacterial, and antihelmintic activity. Thus, jaggery prepared using plant mucilage as clarificants is a novel nutraceutical product which can supplement the nutrients along with various medicinal properties through antioxidant, antibacterial, and antihelmintic activity.