Objective To emphasize the role of apheresis in management of pancreatitis. Methods The clinical course of a patient admitted for hypertriglyceridemia-induced pancreatitis (HTGP) complicated by multiorgan dysfunction is described, who demonstrated dramatic improvement in his clinical status after total plasma exchange (TPE). In addition, the current guidelines for TPE and the alternative treatment options for HTGP are also presented. Results A patient presenting with pancreatitis associated with severe systemic inflammatory response was admitted to our hospital with an initial triglyceride level of 1181 mg/dL. Given the patient's worsening clinical condition, he was started on TPE with a rapid fall in his serum TG levels, in turn leading to early clinical recovery. Conclusion Though various therapeutic options for the treatment of HTGP are described in literature, there are no set guidelines available to tackle this difficult clinical situation. TPE, albeit not very well known in this context, is one of the many therapies available. Though it leads to a rapid, precipitous fall in the TG levels and early symptom resolution, the data about the long-term morbidity as well as the effectiveness of this therapy is still lacking.

Objective: To present a case of papillary thyroid cancer (PTC) with radioiodine (RAI) uptake in a benign renal cyst on the posttherapy whole-body scan (pT-WBS).Methods: The clinical course and diagnostic findings are described for a patient with PTC postthyroidectomy, who was found to have RAI uptake in a benign renal cyst after thyroid remnant ablation (TRA). In addition, a literature review regarding iodine uptake in nonthyroidal tissues is presented.Results: With a negative diagnostic scan for PTC postthyroidectomy, our patient underwent RAI TRA with subsequent unexpected uptake in the left posterior upper quadrant of the abdomen on the pT-WBS. Single-photon emission computed tomography/computed tomography imaging delineated the area to the left kidney. On further sonographic imaging, a simple cyst was seen in the suspected area, with no evidence of metastatic lesions.Conclusion: RAI has been used diagnostically to recognize, as well as therapeutically treat, thyroid remnants and distant iodine-avid metastases postsurgery. Rarely however, iodine may be taken up by various normal, nonthyroidal tissues, including thymus, breast, liver, and gastrointestinal tract, or under conditions such as the presence of cysts or inflammation. It is worth considering these processes in the evaluation of unanticipated iodine uptake to prevent potential unnecessary evaluation and testing.

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