Background: One of India's biggest public health issues is malaria. Malaria is frequently linked to poverty, but it also contributes to it and hinders economic growth. The risk affects approximately half of the world's population (3.3 billion), making it the sixth largest cause of mortality globally. Objectives: The study's goal was to determine the function of a set of predetermined homoeopathic medications in the treatment of malaria. Methods: Out of 180 assessed cases, 36 individuals in all were enrolled. The research included patients who had the typical clinical signs and symptoms of malaria and had tested positive for the malaria parasite in a blood test. Based on typical malaria symptoms, experimental medications were chosen from the mainstream homoeopathic literature. Using a student t test calculator online, statistical analysis was performed. p value less than 0.05 recognized as a significant. Results: Of 36 individuals who tested positive for malaria, the majority (41.66%) had temperatures over 102°F. Just 8 patients had palpable spleens. (22.22%) In 21 individuals, mild body & muscular aches were detected. (58.33%). 22 individuals had mild fatigue and moderate sweating. ( 20) and (61.11%), respectively. Thirteen individuals (36%) reported experiencing nausea and vomiting. The mean MSS score at the beginning of the treatment was 12.2±1.6, and at the conclusion it was 6.9±3.4 (p 0.05). ESR value decreased as well and results were statistically significant. According to indications, the most often given medications were arsenic album (n=12, 33.33%),