ABSTRACT. We report herein a case of multicentric myelolipoma in an 11-year-old beagle dog that presented with vomiting. Laparotomy demonstrated the presence of a large mass adherent to the greater omentum and multiple small white maculae in the spleen. Cytological and histological examinations revealed that the mass and maculae comprised mature adipocytes and hematopoietic elements including granulocytic, erythrocytic and megakaryocytic series in several phases of maturation and macrophages containing hemosiderin deposits, resembling bone marrow. Multicentric myelolipoma was diagnosed. This is first report of multicentric myelolipoma in a dog.
Long-term administration of glucocorticoid had aggravated the skin lesions in a Golden Retriever with chronic refractory pruritic dermatopathy. The skin biopsy revealed cutateous calcinosis with intence inflammatory reaction suggesting iatrogenic Cushing's syndrome. Discontinuance of the glococorticoid administration resulted in remarkable improvement of the skin lesions as well as pruritis.
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