In this paper, the influence of moisture sorption and desorption of walls on space conditioning load is evaluated by dynamic simulation based on detailed building physics taking account of heat and moisture transfer and airflow of whole buildings. Then sensitive analysis is performed with a number of factors, such as preset temperature and humidity of space conditioning, ventilation amount, property of interior materials and so on, which influence indoor humidity. Eleven factors that affect indoor humidity are defined with the extent of the influence by the multiple regression analysis on the basis of the sensitive analysis. It is clarified that the moisture sorption and desorption of walls are influence both heating and cooling load at a rate over 10 percent and water vapour permeance and moisture capacity of interior finish are the significant factor on the moisture sorption and desorption.

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