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Because few prospective studies have addressed this issue, this study examined the relation between DM type 2 and leukocyte count, ESR, BMI, BP. Total and differential WBC count, ESR. BMI and blood pressure for 250 participants: 91 men and 159 women. Among 91 men there are 62 diabetic, and among 159 female subjects, 110 develop diabetes were measured. All using data were collected from diabetic Hospital. In the present work a graded association between higher WBC and diabetes mellitus type 2 was observed after adjusting for age, sex. ESR, BMI, and BP were also significantly associated (P < 0.05) with DM type 2. Smoking status has no real effect in the present data. These finding are consistent with the hypothesis that an activation of leukopoiesis may play a role in pathogenesis of DM type 2 and the inflammation is a dependent risk factor for diabetes. Additional studies are needed to determine whether circulating levels of inflammatory markers are associated with increased risk of incident diabetes.

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