No abstract

No abstract

NEW ScrZ~/rzo~zeZZn TYPE FROM HOGS 395 fapyridine at both room and body temperatures was essentially the same as that of the respective controls. Neither the age of the specimen nor donor altered either susceptibility or resistance to these drugs. The results were equally negative if the sulfanilamide and sulfapyridine were added to Baker's solution plus semen or to undiluted semen.Since an in vitro concentration o f as much as 160 mg % was used, these results gain added significance when it is recalled that the maximum tissue fluid concentration of sulfanilamide achieved clinically is about 15 mg and that of sulfapyridine a b u t 1 0 m g %.Sumnzcwy : In z&o concentrations of sulfanilamide and sulfapyridine well above the tissue concentration achieved by therapeutic doses, do not affect the survival or activity of human spermatozoa. 11466