In this study, patients with CAE had a decreased SOD plasma activity and an increased GGT activity compared with normal controls. These results suggest that oxidative stress and antioxidant status may have an important role in the pathogenesis of CAE.
A AB BS ST TR RA AC CT T O Ob bj je ec ct ti iv ve e: : Tricuspid regurgitation is a common finding in healthy subjects. This finding may associate with patent foramen ovale that it is relatively common in the community. No study was found investigating the association between tricuspid regurgitation and patent foramen ovale. The aim of this study was to evaluate the association between tricuspid regurgitation and patent foramen ovale in healthy young subjects. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : Eighty-eight subjects were included in the study. Subjects who had evidence of cardiovascular or other systemic disease were excluded from the study. Detection of tricuspid regurgitation was performed with color flow Doppler. The tricuspid regurgitation jet length and area were measured using color Doppler images. The tricuspid regurgitation jet peak velocity and duration were measured with continuous wave Doppler modality. Study subjects were divided into two groups according to whether patent foramen ovale was present [PFO (+) group and PFO (-) group]. R Re es su ul lt ts s: : There were 23 subjects in the PFO (+) group and 65 subjects in the PFO (-) group. Tricuspid regurgitation flow was pansystolic in 70% of subjects in the PFO (+) group and 8% of subjects in the PFO (-) group (p<0.001). Sensitivity and specificity pansystolic tricuspid regurgitation for detecting patent foramen ovale were 70% and 92% respectively. C Co on nc cl lu us si io on n: : Our data indicate that pansystolic tricuspid regurgitation associated with patent foramen ovale in healthy individuals. Pansystolic tricuspid regurgitation has high specificity and sensitivity for detecting of patent foramen ovale.K Ke ey y W Wo or rd ds s: : Foramen ovale, patent; tricuspid valve insufficiency Ö ÖZ ZE ET T A Am ma aç ç: : Sağlıklı bireylerde triküspid yetersizliği sık rastlanan bir bulgudur. Bu bulgu toplumda göreceli olarak sık görülen patent foramen ovale ile ilişkili olabilir. Patent foramen ovale ve triküspid yetersizliğini araştıran herhangi bir yayına rastlamadık. Çalışmamızın amacı, sağlıklı genç erişkinlerde patent foramen ovale ve triküspid yetersizliği arasındaki ilişkiyi araştırmaktır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Sağlıklı 88 birey çalışmaya alındı. Kardiyovasküler veya başka bir sistemik hastalığı olanlar çalışmaya alınmadı. Triküspid yetersizliği renkli Doppler ekokardiyografi ile saptandı. Triküspid yetersizlik akımının uzunluğu ve alanı renkli Doppler görüntülerden elde edildi. Triküspid yetersizlik akımının zirve hızı ve süresi devamlı Doppler spektral görüntülerden ölçüldü. Çalışma vakaları patent foramen ovale olup olmadığına göre PFO (+) grup ve PFO (-) grup olmak üzere 2 gruba ayrıldı. B Bu ul lg gu ul la ar r: : Çalışma kriterlerine uyan 88 vakanın 23'ü PFO (+) grupta ve 65'i PFO (-) grupta idi. Triküspid yetersizlik akımı PFO (+) gruptaki vakaların %70'inde pansistolik iken bu oran PFO (-) grupta %8 idi. Patent foramen ovalenin saptanmasında pansistolik triküspid yetersizliğinin özgü...
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