n-Butyl-2-cyanoacrylate had no significant effect on tensile strength. However, its application on the suture line provided extra pressure resistance ex vivo. We believe that further studies need to be conducted to investigate its long-term effects and histological impact on tracheal anastomoses in vivo.

No abstract

The aim of this study was to evaluate the histopathological impact, effectiveness, and safety of two hemostatic agents, Ankaferd Blood Stopper (ABS) and microporous polysaccharide hemospheres (MPH), in an experimental rabbit epistaxis model. Rabbits were randomly assigned, using a computerized random number generator, to the following three groups of six animals: group 1 (control, irrigated with saline); group 2 (ABS-treated); and group 3 (MPH-treated). In all groups, a standardized rabbit epistaxis model was used. Hemostasis time and extent of nasal bleeding were measured to compare the hemostatic effect of ABS and MPH among groups. Septums were removed for histopathological analysis, 7 days after the procedure. ABS reduced hemostasis time to 104.2 s and amount of bleeding to 20.5 mg. MPH reduced hemostasis time to 71.7 s and amount of bleeding to 11.5 mg. Mean bleeding time in wounds administered ABS and MPH was significantly shorter compared with wounds administered isotonic saline solution (p = 0.004). ABS and MPH application decreased bleeding significantly compared with the control group (p = 0.004). Bleeding time and amount in the MPH group was significantly reduced compared with the ABS group (p = 0.013 and p = 0.004, respectively). There was no significant difference in the histopathological evaluation results between the ABS, MPH, and control groups. Our data indicate that both ABS and MPH represent safe, effective, and fast-acting hemostatic agents in the management of epistaxis. MPH was more effective than ABS in terms of hemostasis time and amount of bleeding.

The use of NBCA and MS comonomer increased the inflammation in rat tracheal anastomosis with respect to inflammatory cell count and epithelial regeneration. So the use of NBCA and MS comonomer in tracheal surgery cannot be recommended yet in the light of our data.

Bu çalışmanın amacı Kulak Burun Boğaz Kliniğine başvuran ve "kıkırdak greft butterfly miringoplasti" ameliyatı yaptığımız kronik otitis medialı hastalarda işitme düzeyini retrospektif olarak analiz etmektir. Yöntemler: Çalışmaya 22 hasta (26 kulak) dahil edildi. 18 hastada genel anestezi altında 8 hastada lokal anestezi altında, gerçekleştirildi. Cerrahi 22 hastada tek kulakta 4 hastada her ki kulakta ve Eavey tarafından tarif edildiği şekilde gerçekleştirildi. Ameliyat öncesi ve ameliyat sonrası yapılan odyolojik incelemeler retrospektif olarak analiz edildi. Bulgular: Çalışmaya dahil edilen 22 hasta (26 kulak)' nın yaşları 12-44 arasında idi. Postoperatif takipte kıkırdak greft butterfly tekniği uygulanan 26 kulağın perforasyonunun kapandığı görüldü. Hastaların odyolojik incelemesinde ameliyat öncesi hava kemik aralığı (ABG) ortalama 14,81±4,12 dB iken, ameliyat sonrası ortalama 6,27±4,50 dB olarak ölçüldü. ABG acısından preoperatif döneme göre postoperatif dönemdeki azalmanın istatistiksel olarak anlamlı olduğu görüldü (p<0.05). Sonuç: Kronik otitis medialı hastalarda kıkırdak greft butterfly miringoplasti tekniğinin güvenli, kolay, kısa sürede yapılabilen, küçük ve orta boyuttaki perforasyonlarda uygulanabilecek bir teknik olduğu görüldü.