This study investigated factors affecting the job satisfaction of Omid hospital staff is performed. This research is correlational and cross-sectional study was conducted in 2013 the sample population included all Omid hospital staff. It is also stratified random sampling; 183 people were selected according to Cochran's sampling formula. Methodology: Data also were collected using a standard questionnaire with good validity and reliability, and then to analyze the statistical methods included analysis of variance (ANOVA), T-test and Pearson's correlation coefficient was used. According to these findings, with an average satisfaction rate of pay received (M=9.40) has the lowest levels of satisfaction among employee job satisfaction. Satisfaction with job promotion with a mean (M=10.17) is the next category. On the other hand, with the average job satisfaction (M=22.52) the highest levels of satisfaction among job satisfaction, dedicated to the satisfaction with the supervisor, with a mean (M=21.56) is the next category. Results: These data indicate that job satisfaction and supervisor satisfaction among employees better salary of satisfaction, and satisfaction with the job promotion. Conclusion: In the bivariate analysis also showed that there is a significant difference between job satisfaction and gender, the inverse relationship between job satisfaction and lower-income workers and there, While the relationship between age and job satisfaction, and the other between education level and work experience personnel, and there is no significant relationship between job satisfaction and so on, depending on the type of employment between job satisfaction, and there is no significant difference in terms of marital status.