DNA thermal denaturation has been investigated in aqueous solutions of diethylsulfoxide (DESO) by means of UV-vis and densimetry methods. It is suggested that, on the one hand, the structural change of entire solutions and, on the other hand, a direct interaction of DESO with DNA are responsible for the observed peculiar behavior. The results obtained were compared with those of dimethylsulfoxide (DMSO), also known from literature.

A Gaussian analysis (LinkFit program) was used to deconvolute overlapping absorption bands due to neutral and anionic forms of ascorbic acid (AA). It has been shown that the neutral form of AA predominates in aqueous solutions of AA containing dialkylsulfoxides (DASO) because a hydrogen-bonded complex forms between DASO and AA molecules.

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