Cotton is an economically important natural fiber in the world, whose seeds are used as food and fiber used in the manufacturing of textiles. Cotton is naturally a renewable synthetic fiber which is derived from petroleum. Restriction in conventional breeding program to hereditary change may be because of those of information something like yield revenue and fiber quality of traits. Vitally, the genome representation of the cotton for various traits is the basic need for breeding purposes. The present review discusses the issues of conventional breeding and genomics resources & efforts are utilized to enhance the yield of cotton.

Background: The prevalence of Angiofibroma of juvenile variety is infrequent tumor of nasopharynx7. It grows aggressively and is locally destructive and extends into the cranium as well. Its symptoms usually involve nasal obstruction with or without nasal bleed. Histopathology shows spindle cells scattered between collagen fibers and vascular tissue. MRI and CT angiogram are the two most important investigations used in its diagnosis. Many methods have been used for its excision since ancient times and many researches have been done to control per operative bleeding as it is a vascular tumor. Aim: This study was performed to compare two methods i.e., 1. Carotid artery ligation per operatively and 2. Embolization of the feeding artery pre operatively in order to assess which method is better in controlling per operative bleeding during its excision. Design: Comparative Setting & duration: Department of Otorhinolaryngology, Jinnah Hospital, Lahore from 01st January 2020 to 31st January 2022. Methodology: A group 20 patients were taken having angiofibroma. 10 patients went for pre operative embolization of the feeding vessel of the angiofibroma after localizing the vessel by having MRA. The other 10 patients had their external carotid artery ligated before excising the angiofibroma. The bleeding which occurred during both procedures was quantified by weighing the gauze pieces soaked per operatively , the blood collected in suction bottle and then comparing the values. Results: The 10 patients who had embolization had far more bleeding during excision as compared to the 10 patients who had their external carotid artery ligated per operatively before excision. Conclusion: Results showed that pre operative embolization is not a better procedure to control per op bleeding as compared to external carotid artery ligation during angiofibroma excision. Keywords: Embolization , angiofibroma , per operative ,

Background: Deviated Nasal Septum is one of the pronounced causes of Nasal Obstruction. A number of surgeries are being done since decades to alleviate symptoms. Recent advancement with endoscopes has revolutionized the surgical approach towards minimal invasive procedures. Aim: To analyze the post-op hospital stay and complications in headlight vs. endoscopic septoplasty Study design: The study is Cross sectional Randomized Control Trial. Place and duration of study: We conducted this study in ENT Unit I of Jinnah Hospital Lahore from June 2021 to January 2022. The follow up time was 2 months. Methodology: We performed this study on 30 patients who were diagnosed with Posterior Septal deviation. We randomly divided the patients into two groups. Group A was to undergo trans-nasal trans-speculum (TNTS) septoplasty while group B, endoscopic septoplasty. We analyzed the outcomes in the form of incidence of anterior nasal packing, post-op hospital stays and rate of adhesion formation. Results: We concluded that in Group A, nasal packing was required in 14(93.3%) patients, adhesion formation in 2(13.3%) patients and the mean post-operative hospital stay was 2.13±0.352 days while in Group B, only 3(20%) patients needed anterior nasal packing, none developed post-surgical adhesion formation and the mean postop hospital stay was 1.00±0.000 days. Practical implication: This study delineated that endoscopic septoplasty once mastered is far superior to Endonasal Conventional septoplasty and must be adopted in all public and private sectors to improve cost-effectiveness. Conclusion: We concluded that endoscopic septoplasty is far superior to trans-nasal trans-speculum (TNTS) septoplasty when post-op hospital stays and incidence of nasal packing was concerned in posterior septoplasty. However, there was no statistical difference in terms of post-surgical adhesion formation among the two studied groups. Keywords: Endoscopic Septoplasty, Trans-nasal trans-speculum (TNTS) septoplasty, Deviated Nasal Septum

Background: Among the carcinomas Head and Neck surgeon encounter, carcinoma larynx is amongst the most commons. Thyroid gland is close to larynx so is its risk to be involved by laryngeal malignancies. Removing whole or part of thyroid gland may put the patient at risk of permanent or temporary hypothyroidism and hypoparathyroidism. In recent past a number of risk factors are nominated to predict invasion of thyroid gland by laryngeal malignancies. So, there is a need to re-consider the management of thyroid gland in total laryngectomy. Aim: To justify the management of thyroid gland in advance carcinoma larynx. Study design: The study is cross sectional Randomized Control Trial. Place and duration of study: We conducted this study in ENT Unit I of Jinnah Hospital Lahore from June 2021 to May 2022. Methodology: A total of 20 patients were included in this study and were randomly divided into two groups on the basis of management of thyroid gland. Group A underwent hemi thyroidectomy while thyroid sparing total laryngectomy was done in group B. Histological evaluation of thyroid Gland was done in group A in addition to analysis of local recurrence in both Groups. Mean duration of follow-up was 6 months. Data analysis was done by using SPSS software and is presented in tabulated forms as percentages. Results: The study showed that thyroid gland was not involved in all cases of advance laryngeal malignancies thus obviating the need of total or hemithyroidectomy in all patients with advance Squamous Cell Carcinoma Larynx. Practical implication: All the cases of advance laryngeal malignancies used to undergo total or at least hemithyroidectomy as bystander of total laryngectomy. This study helps the surgeon decide whether a patient with proven laryngeal malignancy needs thyroid gland manipulation or not, thus decreasing the morbidity of the patient and improving cost effectiveness. Conclusion: This study made us reach to the conclusion that in patients with Grade I and II SCC, with no clinical or radiological involvement of thyroid and cricoid cartilage, thyroid gland, strap muscles or skin, there is no need for manipulation of thyroid gland in patients undergoing total Laryngectomy. Keywords: Laryngeal Carcinoma, Thyroid Gland management, Total Laryngectomy with Hemi thyroidectomy,

Background: The prevalence of Angiofibroma of juvenile variety is infrequent tumor of nasopharynx7. It grows aggressively and is locally destructive and extends into the cranium as well. Its symptoms usually involve nasal obstruction with or without nasal bleed. Aims: To compare two methods i.e 1. Carotid artery ligation per operatively and embolization of feeding artery pre operatively in order to assess which method is better in controlling per operative bleeding during its excision. Design: Comparative study Study setting: The study was conducted in the Department of Otorhinolaryngology of Jinnah Hospital, Lahore. The duration of the study is from 01st January 2020 to 31st January 2022. Methodology: A group 20 patients were taken having angiofibroma. 10 patients went for pre operative embolization of the feeding vessel of the angiofibroma after localizing the vessel by having MRA. The other 10 patients had their external carotid artery ligated before excising the angiofibroma. The bleeding which occurred during both procedures was quantified by weighing the gauze pieces soaked per operatively, the blood collected in suction bottle and then comparing the values. Results: Ten patients who had embolization had far more bleeding during excision as compared to the 10 patients who had their external carotid artery ligated per operatively before excision. Conclusion: Results showed that pre operative embolization is not a better procedure to control per op bleeding as compared to external carotid artery ligation during angiofibroma excision. Keywords: Embolization, angiofibroma, per operative ,