Vegetable breeding is one of the most important ways to ensure food security. The current study was conducted on five inbred lines to obtain 10 F1 pickling cucumber hybrids using half diallel mating design. The results indicated that high significant differences between all genotypes compared with check in all studied traits. In addition to, significant general (GCA) and specific combining ability (SCA) effects for all studied traits. The ratio GCA / SCA was less than unity, which indicates that the non-additive genetic variance component. Furthermore, some genetic parameters were revealed that two parents (P5 and P2) were good general combiners for most traits. The five crosses (P1 × P3), (P1 × P4), (P3 × P4), (P3 × P5), and (P4 × P5) exhibited significant desirable positive SCA in all commercial traits which effective on economic productivity. Most of these hybrids gave significant heterosis values over mid and high parents in vegetative, flowering, early, and total yield characteristics. Generally, the parent (P5) could be used as a promising progenitor for all commercial traits in addition to genetic improvements by hybridization.