Vesignieite, Cu3Ba(VO4)2(OH)2, crystallizes in space group C2/ m with a ° = 1.0270(2), b ° =0.5911(1), c° = 0.7711(2)nm and β =116.42(3)°. The intensity data were collected with the RIGAKU RASA‐IIS single‐crystal four‐circle diffractometer. The structure was determined by Patterson and Fourier methods and refined by the least‐square technique to a final R index of 0.051 for 614 independent diffraction points with |F| > 3σ| F|.The crystal structure analysis shows that vesignieite has a layer structure parallel to (001).The powder diffraction lines were reindexed.