This study suggests that a self-administered questionnaire can be used in an older adult population to identify patients potentially at increased risk of MRPs. Clinicians in ambulatory care settings with similar patient populations can use a modified form of the questionnaire to screen for patients who should receive a medication review.

Although no criteria may ever be globally applicable, STOPP and START make significant advances. Regional drug availability, economic considerations, and clinical practice patterns impact criteria selection. Research to validate the several newer criteria in various practice settings and to explore the effect of adhering to the guidelines on patient outcomes is warranted. Data from such research will aid practitioners in identifying preferred criteria.

This study supports the validity of the 8-item version of the Medication-Risk Questionnaire (MRQ8). The MRQ8 can identify higher-risk patients via family caregivers and target them for medication review and other preventive intervention. It also enables pharmacists to collaborate with family caregivers in identifying older adults at high risk for medication-related problems.

Routine CoQ10 supplementation for all patients taking statins to prevent myotoxicity is not recommended. However, certain subpopulations might be at risk and warrant further study.