This experiment was carried out to investigate the best spray timing for the control of the bacterial shot hole with Bordeaux mixture (6-6) after wintering in the peach orchard. We sprayed Bordeaux mixture (6-6) on 'Mibaekdo', 'Yumyeong' and 'Cheonhong' of peach verities from late-March to mid-April in 2001, 2002 and 2014, and examined how much bacterial shot hole and chemical injure occurred. The infection rate of bacterial shot hole according to spray time was 10.2 to 11.7% at leaves, and 1.7 to 2.2% at fruits in 2002. And Efficacy of the Bordeaux mixture treatment for control of bacterial shot hole at full blooming time 21.2 to 30.4% at leaves, 1.7 to 4.4% at fruits in 2014. The chemical injure occurred slightly for one week hence. The fruit bearing rate was 20.7 to 29.8% at 'Mibaekdo', and 35.4 to 61.9% at 'Yumyeong' peach trees. When the spray at the time of blooming period by bordeaux mixture was investigated the control effect of bacterial shot hole disease. The infected leaves was better than 21 to 25% twice the quantity of finished products and bordeaux self-preparation about 28 to 30% base quantity of finished products, also the control efficacy was higher in infected fruits trends in bordeaux self-preparation method and twice the quantity of finished products.