This comparative analysis was done to assess cancer data on Filipinos in the Philippines and migrant Filipinos, to review the trends of cancer incidence with emphasis on oral cancer on both populations and to recommend needs based on findings. The current data on oral cancer in the Philippines revealed varying results on the reported incidences within the country. The country is evolving as a new oral cancer hotspot in Southeast Asia. A general trend of increase in oral cancer and general cancer incidence rates among migrant Filipinos for both sexes was seen when compared with home country values. The urgent need for additional epidemiological and experimental data and research on other regional areas of the country as well as other top destinations for Filipino migrants was seen to fully supplement the current available cancer data.