The aim of this systematic review with meta-analysis was to compare the effect of Silver Sulfadiazine (SSD) with other new dressings, with or without silver, on healing and infection prevention in burns. The electronic search was carried out in the electronic databases of Pubmed, ScienceDirect, Lilacs and BVS. The articles included were randomized clinical trials about burn treatment with SSD, which evaluated the healing and infection of burn wounds in humans. The exclusion criteria included articles, editorials and letters published in the form of abstracts, unpublished reports and case series, cross-sectional, observational experimental studies, and the use of sulfadiazine for other types of wounds. The search identified 873 references, and 24 studies were included in accordance with the eligibility criteria. The results showed a statistically favorable difference related to the time of healing for silver dressings (p<0.0001; MD 3.83; 95% CI 2.03-5.62) and dressings without silver (p<0.007; MD 2.9; 95% CI 0.81-5.00) in comparison with SSD. The rate of infection showed no difference in the group treated with SSD compared with the group treated with dressings containing silver (p>0.05). The rate of infection was significantly higher in the SSD group compared with the group treated with dressings without silver (p<0.005; MD 25.29% and MD 12.97%). Considering the clinical trials conducted up to the present time, the authors concluded that new dressings with and without silver show better results than SSD for wound healing, and burns treated with dressings without silver are less likely to become infected than burns with SSD. No differences between SSD and new silver materials were observed in relation to infection prevention.

Background : New methods of surface modification have been studied with promising results. Among these, the surface modification by laser beam stands out, which has the advantage of clean processing with a high degree of purity, in addition to being executed in a controlled and reproducible way. Aim/Hypothesis : The aim of this study was to characterize the surface of dental implants (cp-Ti) modified by laser beam surface with or without hydroxyapatite deposition and compare with maCHINAd surface and sandblasting followed acid conditioning surface commercially available. Materials and Methods : The surface employed in this study were laser beam surface (LS), laser beam surface with hydroxyapatite deposition (LHS), maCHINAd surface (MS) and sandblasting followed acid conditioning surface commercially available (SES). Topographic characterization was performed by scanning electron microscopy coupled to the x-ray dispersive energy spectrometry system (SEM-EDX), roughness, cross-sectional roughness, contact angle, X-ray diffraction (XRD) and laser confocal optical perfilometry. The data obtained by the roughness statistical analysis. Results : The SEM of LS and LHS showed rough surfaces with a more regular and homogeneous morphological pattern. MS showed smooth surface, contaminated with machining residues while SES presented morphological pattern of craters, with peaks, and valleys of different depths and sizes. The EDX showed Ti peaks and great peaks of oxygen for LS and SS. The MS presented only peaks of Ti and SES Ti peaks and small peaks of O. The mean roughness values of LS and SS were statistically higher (P < 0.05) than MS and SES. The roughness values in cross section were 21.76 ± 9.05 μm and 35.31 ± 9.77 μm respectively for LS and LHS while cross section of SES and MS were 2 ± 1 μm 0.43 ± 0.19 μm respectively. The contact angle of LS and LHS was 0º, allowing high wettability. The XRD of MS nad SES showed only Ti peaks, while LS and LHS showed the presence of oxides and nitrides and presence of hydroxyapatite. Conclusions and Clinical Implications : In view of the results obtained, it was concluded that the texturizations performed in the LS and LHS implants promoted important modifications in the topography and physical-chemical properties. Acknowledgements : The authors would like to thank so much Titanium-Fix-AS Technology for implants and disks and would like FAPESP

Conclusion and Clinical Implications : Despite the limitations of the study, our findings showed that NDI can be considered as a possible alternative treatment with promising survival rates. However, longer follow-up studies are needed to confirm these results.

Background and Aim Methods and Materials

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