A rare case of extremity gangrene caused by accidental injection of haloperi dol, diazepam, and chlorpromazine in the ulnar artery is presented. The intra- arterial injection of drugs and its complications could be avoided by scrupulous selection of site, away from the cubital fossa. A free-flowing intravenous line should be established before any intravenous injection of medications is at tempted. This decreases any chance of such an incident. Expeditious measures to counteract the injected drug could minimize the complications.