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Mostly by cDNA cloning, well over 20 significantly related, GTP-binding proteins have been identified in mammalian cells. According to distinct structural features, these proteins, constituting the ras superfamily, can be separated into at least three families: ras, rho and ypt proteins (1). The genomic sequences of the H-, K-, N-and Rras genes only have been elucidated (2,3,4,5). Here we present the genomic sequence of the mouse yptl gene which

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