-Quality of life (QoL) is an important treatment outcome indicator in Parkinson's disease (PD). the aim of this study is to assess the usefulness of the Parkinson's disease questionnaire -PDQ-39 (Brazilian Portuguese Version) in measuring QoL of PD patients with or without motor fluctuations. Fifty-six PD patients with mean disease duration of 7.4 years were assessed and 41 of them (73.3%) had motor fluctuations. the PDQ-39 has eight dimensions ranging from 0 to 100; being the higher the score, the worse the QoL. comparing groups with and without motor fluctuations showed that the dimensions mobility, activities of daily living (ADL), communication and bodily discomfort scored higher in the fluctuating group. there was a tendency to see that the higher the Hoehn and Yahr (HY) scale stages, the higher the PDQ-39 scores. Patients suffering from the disease for more than five years had worse PDQ-39 scores only in the items ADL and communication, when compared with those with the disease for ≤ 5 years. the PDQ-39 is an instrument that detects decrease in QoL of PD patients and the presence of motor fluctuations predicts QoL reduction.KeY worDs: Parkinson's disease, quality of life, psychomotor performance, levodopa Escala para qualidade de vida na doença de Parkinson -PDQ 39 (versão do Português falado no Brasil) como instrumento para avaliação de pacientes com e sem flutuação motora decorrente da levodopa resumo -A qualidade de vida (QdV) é um item importante para se mensurar o sucesso do tratamento na doença de Parkinson (DP). o objetivo deste estudo foi o de avaliar a utilidade do questionário sobre a doença de Parkinson -PDQ-39 (versão em língua portuguesa falada no Brasil) para mensurar a QdV dos pacientes parkinsonianos com e sem flutuação motora. Nós avaliamos 56 pacientes com DP com tempo médio da doença de 7,4 anos, e destes 41 (73,3%) apresentavam flutuação motora. A PDQ-39 tem oito domínios que variam de 0 a 100 e quanto maior o escore pior a QdV. A comparação dos grupos de pacientes com e sem flutuação motora mostrou que os domínios: mobilidade, atividades de vida diária, comunicação e desconforto corporal tinham escores maiores nos flutuadores. Quanto maiores os estágios de Hoehn e Yahr (HY) da doença, maiores os escores da PDQ-39. Pacientes com mais de 5 anos de evolução da doença mostraram escores piores da PDQ39 apenas nos itens atividades da vida diária e comunicação se comparados a pacientes com 5 anos ou menos de doença. A PDQ-39 é um instrumento capaz de detectar declínio da QdV de pacientes com DP e a presença de flutuação motora é um preditor para redução na QdV. Parkinson's disease (PD) ranks second in prevalence of degenerative disease of the nervous system, after Alzheimer's disease, and it is estimated that 0.3% of population is affected 1 . A recent Brazilian study carried out in the town of Bambuí, state of minas Gerais, Brazil, showed that PD affects 3.3% of individuals aged over 65 years 2 . especially in its initial stages, PD symptoms are mainly motor, later on cognitive dysf...
-Background: Changes in balance occur with the progression of Parkinson's disease (PD). Objective: To validate the Brazilian version of the Berg Balance Scale (BBS) for PD patients, determining its reliability and internal consistency and correlating it with PD-specific instruments. Method: We evaluated 53 patients (M/F 37/16, mean age±SD, 62±7.9 years) with PD (mean±SD, 7.8±4.4 years). Unified Parkinson's Disease Rating Scale (UPDRS), Schwab and England Scale (S&E), Hoehn and Yahr Staging Scale (HY) and BBS were used to assess patients. Statistical analyses for inter-rater reliability, internal consistency and correlations among BBS, UPDRS, S&E and HY were performed. Results: The mean scores±SD on UPDRS and BBS were, respectively, 41.6±17.8 and 47.2±8.2. The median on S&E and HY scales were 80% and 2.5, respectively. The BBS presented a high intraclass correlation coefficient (ICC=0.84) and internal consistency (Cronbrach's α=0.92). There was a statistically significant correlation between BBS and disease duration (r s = -0.520, p<0.001), UPDRS subscales II and III (r s = -0.467, p=0.011; r s = -0.374, p=0.046, respectively), stage of disease (HY; r s = -0.507, p<0.001) and the activities of daily living (S&E; r s =0.492, p<0.001). Conclusion: The BBS is a promising tool for the assessment of balance in PD, correlating with the stage of disease and the level of independence.KEY WORDS: Parkinson's disease, postural instability, Berg Balance Scale. Validação da versão brasileira da Escala de Equilíbrio de Berg para pacientes com a doença de ParkinsonResumo -Alterações de equilíbrio ocorrem com a progressão da doença de Parkinson (DP). Objetivo: Validar a versão brasileira da Escala de Equilíbrio de Berg (EEB) para pacientes com DP, determinando a confiabilidade, a consistência interna e correlacionando com instrumentos específicos da DP. Método: Foram avaliados 53 pacientes (H/M 37/16, idade média±DP, 62±7,9 anos) com DP (media±DP, 7,8±4,4 anos). Escala de Graduação Unificada da Doença de Parkinson (UPDRS), Escala de Schwab e England (S&E), Escala de Estágios de Hoehn e Yahr (HY) e EEB foram utilizadas. Análise estatística para confiabilidade entre examinadores, consistência interna e correlações entre EEB, UPDRS, S&E e HY foram realizadas. Resultados: Os escores médios±DP nas escalas UPDRS e EEB foram, respectivamente, 41,6±17,8 e 47,2±8,2. A mediana nas escalas S&E e HY foram 80% e 2,5. A EEB mostrou ter alto coeficiente de correlação intraclasse (ICC=0,84) e consistência interna (α de Cronbach=0,92). Houve correlação estatisticamente significativa entre EEB e a duração da doença (r s = -0,520, p<0,001), subescalas II e III do UPDRS (r s = -0,467, p=0,011; r s = -0,374, p=0,046, respectivamente), estágio da doença (HY; r s = -0,507, p<0,001), com as atividades da vida diária (S&E; r s = 0,492; p<0,001). Conclusão: A EEB é um instrumento promissor para avaliar o equilíbrio na DP, correlacionando-se com o estágio da doença e o nível de independência.
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