Abstract. An experiment was conducted to produce superior pigs with improved growth phenotypes and survival during postnatal growth by injecting the sows with gonadotropin prior to mating. The experiment consisted of 2 stages. In the first stage, 12 sows were divided into 2 groups i.e., sows injected with NaCl0.95% as a control (NSO) and sows injected with PG600 (SO) prior to mating. Parameters measured were growth phenotypes and survival at birth and during pre-weaning period. In the second stage, 24 of weaned pigs (age 8 weeks) from the first stage were selected (6 males and 6 females from NSO group and 6 males and 6 females from SO group) to be used for measurement of growth performance. The experimental pigs were raised and observed until the age of 28 weeks (7 month). The body weights were measured monthly. The results of the experiment showed that improvement of uterine environment by gonadotropin injection of the sows prior to mating dramatically improved birth weight with a very homogenous birth weight within litter size. Improved birth weight and within-litter variation of birth weight improved pre-weaning growth performance and survival that finally dramatically increased weaning weight and total weight of weaned pigs per sow. After weaning, pigs born to SO sows grew faster and had around 10 kg higher body weight as compared to control at the age of 7 month. It was concluded that superior pigs could be produced by improving endogenous secretion of pregnant hormone during pregnancy.Key words: Birth weight, growth phenotypes, survival, prenatal growth, postnatal growth Abstrak. Penelitian ini dilakukan untuk menghasilkan anak-anak babi unggul dengan fenotipe pertumbuhan dan daya hidup yang lebih baik selama pertumbuhan pascalahir dengan cara menyuntik induk babi dengan gonadotropin sebelum pengawinan. Penelitian terdiri atas dua tahapan. Penelitian tahap pertama, 12 ekor induk babi dikelompokkan ke dalam 2 kelompok, 1) kelompok kontrol, yaitu induk yang disuntik dengan NaCl 0.95% (NSO) dan 2) kelompok yang disuntik dengan PG600 sebelum pengawinan (SO). Parameter yang diukur ialah fenotipe pertumbuhan dan daya hidup anak pada saat lahir dan selama periode prasapih. Tahap kedua, 24 anak babi lepas sapih dari percobaan tahap pertama (umur 8 minggu) dipilih (6 jantan dan 6 betinadari kelompok NSOdan 6 jantan dan 6 betina dari kelompok SO) untuk digunakan dalam pengukuran kinerja pertumbuhan pascasapih. Babi percobaan dibesarkan dan diamati sampai umur 28 minggu (7 bulan). Bobot badan diukur setiap bulan. Hasil penelitian menunjukkan bahwa perbaikan lingkungan uterus dengan cara penyuntikan induk dengan gonadotropin sebelum pengawinan secara dramatis memperbaiki bobot lahir anak dengan bobot lahir per induk yang lebih seragam. Perbaikan bobot lahir dan keseragaman bobot lahir memperbaiki kinerja pertumbuhan prasapih dan kelangsungan hidup anak yang pada akhirnya secara dramatis meningkatkan bobot sapih dan total bobot anak yang disapih per ekor induk. Setelah penyapihan, anak babi yang dilahirkan oleh induk y...
An attempt was made to repair cell-mediated immunity in 7 patients suffering from lepromatous leprosy and severe erythema nodosum leprosum by intravenous infusion of 400 million allogeneic blood lymphocytes on 3 occasions. The lymphocytes were obtained from lepromin and tuberculin-positive subjects and were inactivated in vitro by treatment with mitomycin C. Immunotherapy with inactivated lymphocytes only modified the severity of erythema nodosum leprosum, without altering other aspects of the disease.
A study on Javan rhinoceros (Rhinoceros sondaicus) in Ujung Kulon National Park, Banten was done to monitor the levels of stress in their natural habitat. The study found that glucocorticoid hormone metabolite 3α,11β-dihydroxy-CM from feces was suitable for indicating the levels of stress in Javan rhino. The assessment was done to study stress variations among the three rhinoceros that had different levels of feed intake, as well as to study variations of stress levels in dry and rainy seasons. The result from this study showed that there were fluctuations of 3α,11β-dihydroxy-CM levels in two of the three rhinoceros. These fluctuations reflect the levels of stress associated with energy intake deficit (energy intake per body weight) and water deficit. This research shows that the deficit in energy intake per body weight, and water limitation are among the biggest sources of stress for rhino population. Stress originating from deficit of nutrients from food plan can be overcome by enriching the habitat of the Javan rhinoceros with high nutrient food plants such as stink vine (Paederiascandens), blackboard tree (Alstoniascholaris), and wild ginger (Costusspeciosus). Stress originating from water deficit can be mitigated by opening tracks and ensuring access to permanent year-round water sources.
Coturnix coturnix japonica is one of quail the promising commodities to breding. Health management of poultry in livestock such as quail has problems related to the threat of disease from the environment. Diseases caused by disease agents attack birds resulting in morbidity and mortality so that farmers experience losses. This study aims to determine the effect of injection of two different antigens at different time frames on body weight gain, relative organ weight and erythrocyte profile in 5-month-old male quail. The study used an experimental method of completely randomized design (RAL) with animals as many as 28 male quails divided into 7 groups with 4 replications, namely K0: not injected with antigen, P1: injection SDMD 2%, P2: SDMD injection 2% and ND vaccine, P3 : injection ND and SDMD 2% in week 4, P4: injection vaccine ND, P5: injection SDMD 2% and SDMD 2%, P6: injection treatment ND vaccine and injection ND vaccine. Data obtained by body weight gain, relative organ weight, erythrocyte count, hemoglobin level and hematocrit value. Data were analyzed by Analysis of Variance (ANOVA) using MiniTab17. The results showed that organ weight gain, relative organ weight, heart, heart, pancreas, kidney, lung, spleen, erotrocyte count, hemoglobin level, and hematocrit value were not significantly different (P> 0.05) with control treatment so it can concluded that the effect of antigen injection does not affect the weight gain of organs, the relative weights of the liver, heart, pancreas, kidney, lungs, spleen, the number of erotrosites, hemoglobin levels, and hematocrit values.
Earlier studies of immunologic reconstitution therapy of active lepromatous leprosy patients by repeated infusions of viable allogeneic blood lymphocytes indicated a beneficial effect. In order to avoid cell separation and its associated risks, we attempted to transfer immunity passively into seven seriously ill lepromatous patients by repeated transfusions of fresh blood donated by healthy, but tuberculin and lepromin positive, subjects. The results showed clinical improvement in some cases with the elimination of Mycobacterium leprae, histological reversion and return of immunologic responsiveness.
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