The present paper describes the findings from a preliminary study of the work problems on train drivers in new work situations. The train driver work system is a compound and complex system with many factors. It is not possible to isolate any contributing factor for work problems from the whole system. The effects of the factors for the problems on the train drivers were studied. The major factors were work hour and schedule, work-life balance, driving on the similar route in the same locomotives, behaviors of passengers and fallback strategies of the automatic systems.