Adenoneuroendocrine carcinoma is a very rare form of cervical carcinoma that includes both endocrine and exocrine components. In general terms, these carcinomas progress aggressively and show early metastases due to the neuroendocrine component. The most important criteria related to prognosis is the stage of the disease. Without clearly determined therapeutic protocols this carcinoma is generally seen at earlier ages and causes high mortality. Many radiotherapy and multidrug chemotherapy protocols are used after surgical intervention. Detection of the neuroendocrine component of cervical tumors is achieved through immunohistochemical staining. Herein, we present a woman aged 50 years who was admitted to the hospital with abdominal pain and postmenopausal vaginal bleeding whose examination revealed a cervical tumor. A pathologic examination after surgery resulted as “adenocarcinoma and large cell neuroendocrine carcinoma.” Afterwards, a combined chemotherapy regimen (cisplatin + etoposid) was administered to the patient and 6 months of progress is evaluated in this report.
ÖZETBikornuat uterusta ortaya çıkan endometrial karsinom nadiren rapor edilmiştir. Sunulan olgu 75 yaşında postmenapozal yakınması olan hastada tanımlanmıştır. Daha önce sunulanlardan farkı bikornuat uterusun bir taraftaki boynuzunda endometrial karsinom, diğer taraftaki boynuzunda endometrial polip belirlenmesidir ve bunların her ikisi de postmenapozal kanama nedenidir. Anahtar Kelimeler: Endometrium kanseri, Bikornuat uterus, Endometrial polip, Postmenapozal kanama ABSTRACT Endometrial carcinomas arising in a bicornuate uterus has been very rarely reported before. Our case report has been identified in 75-year-old patient with postmenopausal bleeding. Unlike previously reported cases, our case showed endometrial carcinoma in one horn and endometrial polyp in the other horn of bicornuate uterus, both of which are among the causes of postmenopausal bleeding.
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