Lifecourse transitions from adulthood into older age are particularly complex for transnationalmigrants, bringing additional challenges and opportunities. Adding to the growing literature on ageing and migration, this article illustrates the ways ICTs facilitate the transnational lifecourse transitions of Vietnamese migrant grandparents in Australia through lifecourse digital learning. Research findings highlight the crucial role that digital citizenship plays in supporting migrant grandparents’ adaptation to increasingly mobile lives through practices of digital kinning and digital homing. These practices include using technological tools to maintain social support networks, exchange transnational caregiving, tackle language, navigation, and social integration barriers, and consume culturally relevant media, all of which support migrant identities and belongings. Findings confirm the importance of ICTs in promoting lifecourse digital learning for older migrants who are often stereotyped for their poor learning capacities and ability to adapt to new living arrangements because of their older age.
The current coronavirus disease 2019 (COVID-19) outbreak is alarmingly escalating and raises challenges in finding efficient compounds for treatment. Repurposing phytochemicals in herbs is an ideal and economical approach for screening potential herbal components against COVID-19. Andrographis paniculata, also known as Chuan Xin Lian, has traditionally been used as an anti-inflammatory and antibacterial herb for centuries and has recently been classified as a promising herbal remedy for adjuvant therapy in treating respiratory diseases. This study aimed to screen Chuan Xin Lian’s bioactive components and elicit the potential pharmacological mechanisms and plausible pathways for treating COVID-19 using network pharmacology combined with molecular docking. The results found terpenoid (andrographolide) and flavonoid (luteolin, quercetin, kaempferol, and wogonin) derivatives had remarkable potential against COVID-19 and sequelae owing to their high degrees in the component-target-pathway network and strong binding capacities in docking scores. In addition, the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis showed that the PI3K-AKT signaling pathway might be the most vital molecular pathway in the pathophysiology of COVID-19 and long-term sequelae whereby therapeutic strategies can intervene.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.