Polybutadiene-block-poly(L-glutamate) copolymers were made by anionic polymerization and subsequent ring-opening polymerization of N-carboxyanhydrides and were characterized by NMR, IR, SEC, and circular dichroism. These polymers, when appropriately designed, form so-called "polymersomes" or "peptosomes", vesicles composed of modified protein units. The size and structure of the vesicles are determined by dynamic light scattering, small-angle neutron scattering, and freeze-fracture electron microscopy. It is also shown that the size of the peptosomes does not depend on the pH; that is, the solvating peptide units can perform a helix-coil transition without serious changes of the vesicle morphology.

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Monodisperse oligo(para‐phenyleneethynylene)s (oligoPPEs) were synthesized by a divergent‐convergent synthesis starting from 1,4‐dihexyl‐2‐(3‐hydroxyprop‐1‐ynyl)‐5‐[2‐(triisopropylsilyl)ethynyl]benzene and using the Pd/Cu‐catalyzed alkyne‐aryl coupling. The groups hydroxymethyl (HOM) and triisopropylsilyl (TIPS) function as orthogonal protective groups for the acetylene moieties. The polar HOM group shows a strong impact on the chromatographic behaviour of the products and makes the isolation of pure compounds very easy. The synthesis was pursued up to the nonamer. The oligoPPEs were fully characterised, including absorption and emission spectral data.