In this pilot study, we found that our questionnaire was a valid and reliable self-administered tool for distinguishing individuals with AD from individuals without AD.
A 33-year-old man with a 15-year history of salt cravings and recurrent vasovagal syncope presented to the dermatology department with asymptomatic brown patches on the buccal mucosa (Fig 1) and tanning of his facial skin that developed over the past 4 winter months. He is a life-long nonsmoker. His only oral medication was fluoxetine. He lacked involvement of the genitals, hands, feet, or nails. He denied a family history of similar pigmentation. After diagnostic confirmation, he was started on appropriate therapy with complete resolution of mucosal hyperpigmentation (Fig 2). Question 1: Based on his clinical presentation, what is the most likely diagnosis? A. Laugier-Hunziker syndrome B. Hemochromatosis C. Peutz-Jeghers syndrome D. Addison's disease E. Cronkhite-Canada syndrome Answers:A. Laugier-Hunziker syndrome e Incorrect. Laugier-Hunziker syndrome is characterized by the combination of oral mucosal hyperpigmentation and melanonychia in 50% to 60% of cases. 1 Our patient lacked nail involvement.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.