Alpha-amanitin is considered to be the main toxin present in mushroom species of Amanita phalloides and it is possibly the most deadly of all amatoxins. The aim of this study was to test whether nanocurcumin could revert the hepatic damage in experimentally induced Alpha-amanitin rats, tested with nanocurcumin in following protocols: Group I served as negative control group (PBS @1ml/kg p.o),
Enhanced rate of divorce among most elite couple in metros alarmed a unique social stigma. A man who is full of stresses of life and lost his manhood is accepting his failure and ready to sign paper of divorce in court as an escape route to get rid of his responsibility. Erectile dysfunction (Klaibya) or impotence is emerging as one of the most serious life style and stress related disease. Over exertion, physiological disturbances, lowered level of hormones and strained relationship with partner are the main causes for this disease. The remedial measure of Erectile dysfunction (ED) is still evolving in conventional system of medicine. The search for a perfect aphrodisiac drug specially a herbo-mineral drug that will heighten sexual desire, pleasure and performance has been a continuing cultural quest from ancient era to current times. Therefore, a herbomineral formulation was prepared, which consists of Vanga Bhasma, Ashwagandha (Withania somnifera) Churna and Kapikachhu (Mucuna pruriens) Churna with three Bhavana of each Dhatura (Datura metel) Patra Swarasa and Bhanga (Cannabis sativa) Kwatha to evaluate the clinical effect in 40 male diagnosed patients of Klaibya (Erectile dysfunction). Out of 40 patients Klaibya of 29 completed the full course of trial treatment and 11 patients were dropped out from the study. The result of 29 patients showed statistically significant improvement in some sexual symptoms and seminal parameters.
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