In Egypt, the request for salt fish products has been increasing during many feasts because it is one of Egypt's favorite foods. It has been reported that in certain seasons, these products cause toxicity and even death. Most fish poisonings around the world are known to be caused by elevated histamine levels. Thus, the study assessed the histamine levels of herring and fesikh samples available on the market and established the safety of these products with recommendations for various treatments that may inhibit the production of histamine in herring and fesikh through bacteria and enzyme production. Before manufacturing herring and fesikh, the fresh fish is soaked for one hour in a modified pH solution of 4 by vinegar with the addition of natural substances individually or in combination (such as garlic, onion, hot pepper, or aloe vera) or some chemicals singly (such as edta, nisin, h2o2, formic acid, and so2). The levels of histamine in herring (111 to 138 mg/kg) and fesikh (214 to 279 mg/kg) were unsafe in marketable samples. The histamine levels of herring and fesikh in proposed treatments were safe since they did not exceed 26 mg/kg after 30 days of cold storage for herring or 45 mg/kg after maturity of fesikh. The proposed treatments enhanced greatly herring and fesikh organoleptic qualities, especially those containing natural ingredients, such as garlic, hot pepper, or their mixture beside onion, which are more accepted treatments.