Tapak liman (Elephantopus scaber L) is one of the traditional medicinal plants, which are containing several active compounds that potentially affecting hematopoietic. The aims of this study are to elucidate the effect of leaf extract of Tapak Liman on hematopoietic in mice BALB/c, by observation on relative number of cells expressing CD4/CD8, CD4/CD62L, and TER119/B220 in the spleen; TER119/B220, TER119/VLA-4 and TER119/CD34 in bone marrow, after given the leaf extract for 2 weeks. This experiment was used 12 female mice, which is divided on 3group treated with leaf extract of Tapak Liman (P 1 = 0.5 g. g bw-1 .day-1 , P 2 = 1.0 g. g bw +), in spleen and bone marrow.

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