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Incidence of abnormality in liver functions was significantly higher in patients with peptic ulcer than in the control group. It was also significantly different from that in patients with gastric cancer or gastritis. The disturbance of liver functions in peptic ulcer was usually mild to slight in degree. No definite correlation was found between liver functions and histological findings on biopsy specimens obtained from 19 randomly selected patients with peptic ulcer. Abnormality in liver function tests is often found in patients with various diseases of the alimentary tracts. Although numerous reports are available,1-12 particularly regarding the cases with peptic ulcer, the importance of the findings has not been fully appreciated.

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