A newly synthesized juvenile hormone active cornpound, S-311S3 (2-[1-methyl-2-(tl-phenoxyphenoxy)ethoxy]pyridine) xvas evaluated for its inhibition of emergence of adult Culex PiPiens Pattens, AnoPheles stePhensi, Aedes aegyPti and Musca domestica in the Iaboratory. It was more active than methoprene, diflubenzuron, or temephos against last instar larvae of Cx. p. pallens, An. stephensi and Ae. aegypti. S-31183 was n]ore active than methoprene and diflubenziiron a.craitist 4-day-old larvae of Af. donzestica in the artificial medium, and inore active than rnethoprene against e.crgs and 4-day-old larvae of A4. domestica in the chicken manure medium.

The first synthesis of (+)‐pisatin [(+)‐11] was achieved by resolving (±)‐6, which in turn was prepared from the isoflavone derivative 1. The unnatural (‐)‐pisatin [(‐)‐11] was also synthesized.

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