Hirotoshi Oinuma scite author profile

Two taraxastane-type hydroxy triterpenes, taraxasterol and faradiol, isolated from the flowers of Compositae plants Cynara scolymus (artichoke) and Chrysanthemum morifilolium (chrysanthemum), respectively, showed strong inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice. At 2.0 µmol/mouse, these compounds inhibited markedly the tumor-promoting effect of TPA (1 µg/mouse) on skin tumor formation following initiation with 7,12-dimethylbenz[Α]anthracene (50 µg/mouse).

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Inhibitory Effect of Di- and Trihydroxy Triterpenes from the Flowers of Compositae on 12-.OMICRON.-Tetradecanoylphorbol-13-acetate-Induced Inflammation in Mice.

Yasukawa

Akihisa

Oinuma

et al. 1996

Biological & Pharmaceutical Bulletin

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Erythro-hentriacontane-6,8-diol and 11 other alkane-6,8-diols from Carthamus tinctorius

Akihisa¹,

Oinuma²,

Tamura³

et al. 1994

Phytochemistry

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Infection Status of Ayu and Other Wild Fish with <i>Flavobacterium psychrophilum</i> and <i>Edwardsiella ictaluri</i> in the Tama River, Japan

et al. 2016

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