The dispersion characteristics of As2S3 solid-core photonic crystal fibers were investigated with the change of structural parameters including filling factor ( ) and lattice constant ( ). Photonic crystal fiber obtained diverse dispersion including all-normal and anomalous dispersion with two zero-wavelengths dispersion at all values of lattice constant investigated. The dispersion value increases when the lattice constant increases and the filling factor decreases. Photonic crystal fiber has a flat dispersion curve and closeness to the zero-dispersion curve in the long-wavelength range are advantages of this design. Based on the analysis of numerical simulation results, we have proposed two structures with optimal dispersion for the application of supercontinuum generation.