A Bayesian framework is used to calibrate a mass-action model of receptor-mediated apoptosis. Despite parameter non-identifiability and model ‘sloppiness', Bayes factor analysis discriminates between two alternative models of mitochondrial outer membrane permeabilization.

Widespread use of affective sensing in healthcare applications has been limited due to several practical factors, such as lack of comfortable wearable sensors, lack of wireless standards, and lack of low-power affordable hardware. In this paper, we present a new low-cost, low-power wireless sensor platform implemented using the IEEE 802.15.4 wireless standard, and describe the design of compact wearable sensors for long-term measurement of electrodermal activity, temperature, motor activity, and photoplethysmography. We also illustrate the use of this new technology for continuous long-term monitoring of autonomic nervous system and motion data from active infants, children, and adults. We describe several new applications enabled by this system, discuss two specific wearable designs for the wrist and foot, and present sample data.

-Wearable sensors enable long-term continuous physiological monitoring, which is important for the treatment and management of many chronic illnesses, neurological disorders, and mental health issues.Examples include: diabetes, autism spectrum disorder (ASD), depression, drug addition, and anxiety disorders. In this paper, we present a few mobile health technologies developed by our group and also discuss emerging opportunities as well as existing challenges. . From a cost perspective, the primary goal has been to move health care away from where it is most expensive (clinic, emergency room) and move toward preventative measures and outpatient monitoring. The motivation is to create technologies that will enable us to continuously monitor our health and track our progress in all stages of life and disease.As health monitoring becomes part of the fabric of everyday life, there is a need for technologies that are comfortable, simple to use, unobtrusive, and also provide privacy and security. Wearable sensors, mobile phones, web cameras, and online social networks are all part of the future health support system.Future forms of medical interventions will likely involve not just pharmacology but also electronic devices. For example, a future doctor may "prescribe" a treatment that